Electrospinned bioactive glass/nano hydroxyapatite reinforced polycaprolactone GTR/GBR membranes in periodontics- A review


Review Article

Author Details : Vishnu J. S., Aneesh Alim, Dilshi Ishaan, Basim Burhan K. B., Aswathy Krishna S

Volume : 3, Issue : 2, Year : 2018

Article Page : 55-62

https://doi.org/10.18231/2457-0087.2018.0012



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Abstract

Periodontitis, a chronic inflammatory infectious disease triggered by an interaction between microbial biofilm and host response leading to gingival bleeding, connective tissue destruction , alveolar bone loss and finally causing tooth loss. Periodontal regeneration or restoration is the ultimate goal of any periodontal treatment. This can be achieved by GTR/GBR [Guided Tissue Regeneration/Guided Bone Regeneration] membranes along with bone replacement grafts. With the evolution of Tissue engineering and different generation of GTR/GBR nanofibrous membranes, periodontal restoration or regeneration can be easily and rapidly achieved . Nanofibrous GTR/GBR Membranes can be fabricated using natural or synthetic polymers by different techniques such as Phase separation, Self assembly and Electrospinning [E-spinning]. Of these, E-spinning is the most widely studied technique and also seems to exhibit the most promising results for Tissue Engineering[TE] applications . This review addresses the Electrospinning method of GTR/GBR membrane fabrication using Bioactive Glass [BG]/Nano Hydroxyapatite[nHAP] reinforced polycaprolactone polymer and its advantages and disadvantages.

Keywords: Electrospinning, Guided Tissue Regeneration, Periodontal Regeneration


How to cite : Vishnu J. S., Alim A, Ishaan D, Basim Burhan K. B., Aswathy Krishna S, Electrospinned bioactive glass/nano hydroxyapatite reinforced polycaprolactone GTR/GBR membranes in periodontics- A review. IP Int J Periodontol Implantol 2018;3(2):55-62


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https://doi.org/10.18231/2457-0087.2018.0012


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